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Urologia ; 90(3): 499-502, 2023 Aug.
Article in English | MEDLINE | ID: covidwho-2296046

ABSTRACT

Different strategies have been proposed to treat cytokine storm syndrome (CSS), the final deadly complication of COVID-19. One approach is to target CSS by blocking the interleukin-6 (IL-6) pathway. A promising group of medications blocking the IL-6 pathway is α-blockers, such as prazosin. First, we hypothesized that Panax ginseng, commonly known as ginseng, can be an effective therapeutic agent in preventing CSS due to its blocking activity on alpha-1 adrenergic receptors (α1-AR). Furthermore, we suggested that herbs with 5α-reductase inhibitory effects, such as Saw palmetto, Nettle root, soya, black pepper, and green tea, can have debilitating impacts on pulmonary function since they can lead to impairment of the lung's ability to regenerate. Thus, we encourage the prospective studies to explore the potential effect of herbal medications, with possible beneficial effects for benign prostatic hyperplasia, during the COVID-19 pandemic since they are commonly consumed.


Subject(s)
COVID-19 , Prostatic Hyperplasia , Male , Humans , Prostatic Hyperplasia/complications , Prostatic Hyperplasia/drug therapy , Interleukin-6/therapeutic use , Pandemics , Prospective Studies , Adrenergic alpha-Antagonists/therapeutic use
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